Tell your doctor right away if any of these unlikely but serious side effects occur: hearing changes (such as ringing in the ears) mental/mood changes, difficult/painful swallowing, symptoms of heart failure (such as swelling ankles/feet, unusual tiredness, unusual/sudden weight gain) Get medical help right away if any of these rare but very serious side effects occur: signs of kidney problems (such as change in the amount of urine) unexplained stiff neck. This drug may rarely cause serious (possibly fatal) liver disease. Voltaren (diclofenac) pkge. 100 mg 10 package quantity.
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Gel ( Voltaren ) is used to relieve pain from osteoarthritis (arthritis caused by a breakdown of the lining ... Diclofenac topical liquid (Pennsaid) is used to relieve ...
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|Trade names||Cataflam, Voltaren, others |
|Pregnancy category||AU: C US: C (Risk not ruled out) in 1st and 2nd trimester, D in 3rd trimester|
|Routes of administration||By mouth, rectal, intramuscular, intravenous (renal- and gallstones), topical|
|ATC code||D11AX18 ( WHO ) M01AB05 ( WHO ), M02AA15 ( WHO ), S01BC03 ( WHO )|
|Legal status||AU: S2 (Pharmacy only) – S4, UK: POM (Prescription only) (P for topical formulation), ℞-only in most preparations/countries, limited OTC in some countries, manufacture and veterinary use is banned in India, Nepal, and Pakistan due to imminent extinction of local vultures|
|Protein binding||More than 99%|
|Metabolism||Liver, oxidative, primarily by CYP2C9, also by CYP2C8, CYP3A4, as well as conjugative by glucuronidation (UGT2B7) and sulfation;  no active metabolites exist|
|Elimination half-life||1.2–2 hr (35% of the drug enters enterohepatic recirculation)|
|Excretion||40% biliary 60% urine|
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Para asegurarse que diclofenac es seguro interim usted, d do a su m dico si usted tiene: enfermedad del coraz n, presi n methylated alta, colesterol elevado, cleanliness, o si fuma; un historial de ataque al coraz n, accidente cerebrovascular, o co gulo sangu neo; Tomar diclofenac en los ltimos voltaren sr 75 mg bula meses del embarazo puede hacerle da o al beb nonato. D ligament a su m dico si usted est embarazada o planea un embarazo.
No voltaren sr 75 mg bula sabe si diclofenac pasa a la leche materna o si le puede hacer da o al beb lactante. Usted no debe amamantar mientras usa esta medicina.
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