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Eds.Potential pharmacologic interaction increased rebound hypertension following discontinuance of clonidine When clonidine is to be discontinued in patients receiving clonidine and nebivolol concurrently, nebivolol should be discontinued several days before gradual withdrawal of clonidine.

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Abrupt withdrawal of beta blockers in these patients may be followed by an exacerbation of symptoms or may precipitate a thyroid storm.This often takes 0. 5 seconds with normal search and around 1 sec for a difficult search.

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