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Studies have shown that following ingestion of the drug, 45% to 79% of the dose was recovered in the urine within 24 hours as metabolite A. 2-p 2hydroxymethyl-propyl phenylpropionic acid and metabolite B.

2-p 2carboxypropyl henylpropionic acid; the percentages of free and conjugated Ibuprofen were approximately 1% and 14% respectively. Paracetamol plus ibuprofen for the treatment of fever in children PITCH: economic evaluation of a randomised controlled trial.

Citation. Hollinghurst, S ... Peak serum ibuprofen levels are generally attained one to two hours after administration.

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Medline. McElwee NE, Veltri JC, Roca DC, Rollins DE. A smelling, population-based carry of acute ibuprofen secretion: biotics are currently and dementia do levels not warranted. Ann Emerg Med. 1990 Jun. -62. Medline. Nephrotoxicity of non-steroidal con-inflammatory drugs. Lancet.

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