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Clinical data
Pronunciation/ ˌ ɛ s oʊ ˈ m ɛ p r ə ˌ z oʊ l, - ˈ m iː -, - ˌ z ɒ l / [2]
Trade namesNexium, others [1]
License dataEU  EMA:  by INN, US   FDA: Esomeprazole
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth, IV
Drug classproton pump inhibitor
ATC codeA02BC05 ( WHO )
Legal status
Legal statusAU: S2 (Pharmacy only) UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability50 to 90%
MetabolismLiver (CYP2C19, CYP3A4)
Elimination half-life1–1.5 hours
Excretion80% Kidney 20% Faecal

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Esomeprazole instruction
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Esomeprazole product namesalenia, alton, asector, axagon, axiago, ceso, cronopep, emep, esmolac, esofag, esofag-d, esomac, esomep, esomeprazol, esomeprazolum, esomezol, esonix, esopra, esopral, esopran, esoprax, esoprazol, esoral, esorest, esotac, esotid, esotrax, esoz, espram, inexium, izra, izra-d, lucen, maxima, maxpro, nedox, neksium, neptor, neutraflux, nexe, nexiam, nexiam iv, nexpro, nexum, nexx, nuloc, opton, perprazole, preso, progut, pronex, raciper, raciper-d, sergel, sompraz, ulcratex, zosec
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Concomitant administration of 30 mg esomeprazole resulted in a 45% decrease in clearance of the CYP2C19 substrate diazepam. Concomitant administration of 40 mg esomeprazole resulted in a 13% increase in trough plasma levels of phenytoin in epileptic patients.The esomeprazole component of VIMOVO is a proton pump inhibitor.

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All patients received NEXIUM Delayed-Release Oral Suspension esomeprazole cost uk daily during a two-week, open-label phase of the study. There were 80 patients who attained a pre-specified level of symptom improvement and who entered the double-blind phase, in which they were randomized in equal proportions to receive NEXIUM or esomeprazole cost uk for the next four weeks.pylori in vitro and in clinical infectionssee Indications and Usage 1 and Clinical Studies 14 Clarithromycin Susceptibility Test Results and Clinical/Bacteriologic Outcomes: The baseline H.

pylori clarithromycin susceptibility results and the H. pylori eradication results at the Day 38 visit are shown in Table 8: Includes only patients with pretreatment and post-treatment clarithromycin susceptibility test results Susceptibility Test for Helicobacter pylori: For susceptibility testing information about Helicobacter pylori, see Microbiology section in prescribing information for clarithromycin and amoxicillin.

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