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|Pronunciation||/ ˌ ɛ s oʊ ˈ m ɛ p r ə ˌ z oʊ l, - ˈ m iː -, - ˌ z ɒ l / |
|Trade names||Nexium, others |
|License data||EU EMA: by INN, US FDA: Esomeprazole|
|Pregnancy category||AU: B3 US: C (Risk not ruled out)|
|Routes of administration||By mouth, IV|
|Drug class||proton pump inhibitor|
|ATC code||A02BC05 ( WHO )|
|Legal status||AU: S2 (Pharmacy only) UK: General sales list (GSL, OTC) US: OTC|
|Bioavailability||50 to 90%|
|Metabolism||Liver (CYP2C19, CYP3A4)|
|Elimination half-life||1–1.5 hours|
|Excretion||80% Kidney 20% Faecal|
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The manufacturer states that dosages exceeding 1 mg/kg daily have not been studied in children 1-11 years of age. The esomeprazole uk oral dosage of esomeprazole for the short-term treatment of GERD in adolescents 12-17 years of age is 20 or 40 mg once daily for up to 8 weeks.Because of these drug interactions, clarithromycin is contraindicated for co-administration with certain drugs see Contraindications esomeprazole uk prescribing information esomeprazole uk clarithromycin.
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Most patients improve with discontinuation of the PPI alone in 4 to 12 esomeprazole uk. Serological testing e.Patients receiving esomeprazole remained in remission longer and experienced fewer recurrences than patients receiving placebo; although esomeprazole 10 mg daily provided less benefit than esomeprazole 20 or 40 mg daily, no additional benefit of the 40-mg daily dosage over the 20-mg daily dosage was esomeprazole uk.
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Concomitant administration of 30 mg esomeprazole resulted in a 45% decrease in clearance of the CYP2C19 substrate diazepam. Concomitant administration of 40 mg esomeprazole resulted in a 13% increase in trough plasma levels of phenytoin in epileptic patients.The esomeprazole component of VIMOVO is a proton pump inhibitor.
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If you miss a dose, take it as soon as you remember.See What are the possible side effects of esomeprazole magnesium prescription esomeprazole cost uk called a esomeprazole cost uk pump inhibitor PPI Esomeprazole magnesium delayed-release capsules reduce the amount of acid in your stomach. gastroesophageal reflux disease GERD Esomeprazole magnesium delayed-release capsules may also be prescribed to heal acid-related damage to the lining of the esophagus erosive esophagitis and to help continue this healing.
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All patients received NEXIUM Delayed-Release Oral Suspension esomeprazole cost uk daily during a two-week, open-label phase of the study. There were 80 patients who attained a pre-specified level of symptom improvement and who entered the double-blind phase, in which they were randomized in equal proportions to receive NEXIUM or esomeprazole cost uk for the next four weeks.pylori in vitro and in clinical infectionssee Indications and Usage 1 and Clinical Studies 14 Clarithromycin Susceptibility Test Results and Clinical/Bacteriologic Outcomes: The baseline H.
pylori clarithromycin susceptibility results and the H. pylori eradication results at the Day 38 visit are shown in Table 8: Includes only patients with pretreatment and post-treatment clarithromycin susceptibility test results Susceptibility Test for Helicobacter pylori: For susceptibility testing information about Helicobacter pylori, see Microbiology section in prescribing information for clarithromycin and amoxicillin.
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