When a group of Christian businessmen took to the streets of Dallas
When a group of Christian businessmen took to the streets of Dallas
sheltering up to 75 men and 30 women.
He formalized our 4-phase faith-based rehabilitation program
Allowed the purchase of what is now our men’s shelter
Became our new women and children’s shelter
To be a shelter with a recovery program for single women without children.

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Although increased plasma concentrations (Cmax and AUC0-24 hrs) of desloratadine and 3hydroxydesloratadine were observed (see Table 2) desloratadine, as assessed by electrocardiographic parameters (including the corrected QT interval) clinical laboratory tests, vital signs, and adverse 3-Hydroxydesloratadine Pharmacokinetics in Healthy Male and Female Volunteers 48 mg/kg/day (estimated desloratadine and desloratadine metabolite exposures were approximately 210 times the AUC in humans at the recommended daily oral dose) or in rabbits at doses up to 60 mg/kg/day (estimated desloratadine exposures were approximately 230 times the AUC in humans at the recommended daily oral dose) In a separate study, an increase in pre-implantation loss and a decreased number of implantations and fetuses were noted in female rats at 24 mg/kg (estimated desloratadine and desloratadine metabolite exposures were approximately 120 times the AUC in humans at the recommended daily oral dose) Reduced body weight and slow righting reflex were reported in pups at doses of 9 mg/kg/day or greater (estimated desloratadine and desloratadine metabolite exposures were approximately 50 times or greater than the AUC in humans at the recommended daily oral dose) Desloratadine had no effect on pup development at metabolite exposures were approximately 7 times the AUC in humans at the evaluated in over 2300 patients 12 to 75 years of age with seasonal allergic rhinitis. Desloratadine (clarinex) packing 5 mg 120 the amount of packaging.

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Clinical data
Trade namesClarinex (US), Aerius, Dasselta, Deslordis (EU), others
License dataEU  EMA:  by INN, US   FDA: Desloratadine
Pregnancy categoryAU: B1 US: C (Risk not ruled out)
Routes of administrationOral (tablets, solution)
ATC codeR06AX27 ( WHO )
Legal status
Legal statusAU: S2 (Pharmacy only) CA : OTC UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilityRapidly absorbed
Protein binding83 to 87%
MetabolismUGT2B10, CYP2C8
Onset of actionwithin 1 hour
Elimination half-life27 hours
Duration of actionup to 24 hours
Excretion40% as conjugated metabolites into urine Similar amount into the feces

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Desloratadine other nameclarinex reditabs, clarinex-d
Active substanceclarinex
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