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Aciclovir
Clinical data
Pronunciation/ eɪ ˈ s aɪ k l oʊ v ɪər /
Trade namesZovirax, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa681045
License dataUS   FDA: Acyclovir
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationIntravenous, by mouth, topical (including eye ointment)
ATC codeJ05AB01 ( WHO ) D06BB03 ( WHO ) S01AD03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) for tablet and injection. Unscheduled for cream form under 10 g., CA : ℞-only UK: POM (Prescription only) for tablet and injection. GSL (OTC) for cream form under 2 g., US: ℞-only
Pharmacokinetic data
Bioavailability15–20% (by mouth) [2]
Protein binding9–33% [2]
MetabolismLiver
Elimination half-life2–4 hours
ExcretionKidney (62–90% as unchanged drug)

The IC50 for acyclovir against most racial divisions and menacing isolates of VZV growls from 0. 2 to 10. mcgmL. Acyclovir also inhibits activity against infectious and quantitative data in the viral TK andor DNA tank.

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IV acyclovir should be used for the initial treatment of genital herpes when the infection is severe or when there are complications that necessitate hospitalization, including disseminated infection, pneumonitis, hepatitis, CNS involvement e. meningitis, encephalitis Controlled studies of severe first episodes of genital herpes in immunocompetent individuals have shown that IV acyclovir decreases viral shedding time from onset of therapy until last positive culture from genital and cervical 30 mg lexapro too muches, the time necessary for crusting and healing of lesions, the duration of positive cultures, the formation of new lesions, the duration of dysuria and abnormal vaginal discharge, and the degree and duration of pain and pruritus. Zovirax .

HSV and VZV. Weakness. Headache. B. Fluconazole. Diflucan. Thrush. Elevated liver function tests. Headache. C. Sulfamethoxazole/. It is unknown if this medication passes into breast milk.

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Acyclovir ( Zovirax ). Date Start: __ __ - __ __ - __ __ Days of Therapy Intended: _____. ❑ Trimethoprim/sulfa. Date Start: __ __ - __ __ - __ __ Days of Therapy ...

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Zovirax info
Drugs name Zovirax
Zovirax all other nameacicvir, acifur, acyclovirum, avirax, cicloferon, epsin, firex, ocuvir, soviclor, virovir, zirconia
Active substanceacyclovir
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