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|Pronunciation||Paracetamol: / ˌ p ær ə ˈ s iː t ə m ɒ l / Acetaminophen: / ə ˌ s iː t ə ˈ m ɪ n ə f ɪ n / ( listen )|
|Trade names||Tylenol, Panadol, others |
|License data||US FDA: Acetaminophen|
|Pregnancy category||AU: A US: C (Risk not ruled out)  Not tested but seems to be safe|
|Routes of administration||By mouth, through the cheek, rectal, intravenous (IV)|
|ATC code||N02BE01 ( WHO )|
|Legal status||AU: S4 (Rx), OTC, and unscheduled UK: General sales list (GSL, OTC) US: OTC|
|Bioavailability||63–89%  : 73|
|Protein binding||10–25% |
|Metabolism||Predominantly in the liver |
|Metabolites||APAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI |
|Onset of action||Pain relief onset by route: By mouth – 37 minutes  Buccal – 15 minutes  Intravenous – 8 minutes |
|Elimination half-life||1–4 hours |
|Excretion||Urine (85–90%) |
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pain, the health care provider may first suggest over-the-counter OTC pain medicines such as aspirin NIH external link or acetaminophen NIH external link. Acad Emerg Med. 2014 Opioid-Prescribing Patterns of Emergency Physicians and Risk of Long-Term Use. Michael L. Barnett, M. Andrew R. Olenski, B. and Anupam B. Jena, M. Ph. N Engl J Med. 63-673values of the glucoronosyl tranferases.
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Full Text.his drug should not be used with the following medications because very serious interactions may occur: sodium oxybate.
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As a group, antidepressants and anti-seizure medications may, rarely, worsen depression or cause suicidal thoughts.Read the label carefully for proper dosage, and be careful not to take more than one medication containing acetaminophen, such as some cough and cold medicines.
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Drink alcohol heavily 3 or more drinks a day for men and 2 or more drinks a day for women Author: Healthwise StaffMedical Review: William H. Blahd Jr. MD, FACEP - Emergency MedicineJohn Pope MD - PediatricsKathleen Romito MD - Family MedicineAdam Husney MD - Family MedicineMartin J. Gabica MD - Family MedicineDavid Messenger MD Medical Review: illiam H.
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While you want to minimize drug use as much as possible, the consequences of not taking a medication on the health of the mother and baby usually outweigh any potential risks. To get relief and feel more at ease throughout your pregnancy, check out Dr. Park s recommendations for safe medications while pregnant.Patients were trained to complete the study diary.
At visit 1, qualified patients were randomly assigned 1: ratio according to a computer-generated is ibuprofen good for lung inflammation schedule, to receive a bottle of double-blinded is ibuprofen good for lung inflammation medication containing either 2 tablets of unbranded Excedrin Extra-Strength acetaminophen, 250 mg; aspirin, 250 mg; and caffeine, 65 mg per tablet; Bristol-Myers Squibb Co, New York, NY or 2 identical-appearing placebo tablets to treat the headache pain of 1 acute self-recognized migraine attack.
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